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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source
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Sexual selection and the ascent of women: Mate choice research since Darwin

Science, 2022
Darwin’s theory of sexual selection fundamentally changed how we think about sex and evolution. The struggle over mating and fertilization is a powerful driver of diversification within and among species. Contemporaries dismissed Darwin’s conjecture of a
G. Rosenthal, M. Ryan
semanticscholar   +3 more sources

Flexible Mate Choice

Encyclopedia of Animal Behavior, 2010
Traditionally, investigators and theorists have supposed that mate choice is directional and fixed within a species as well as static within individuals over time.
Malin Ah-King
openaire   +2 more sources

Mate Choice

Encyclopedia of Evolutionary Psychological Science, 2021
openaire   +2 more sources

Mate-Choice Copying

Encyclopedia of Evolutionary Psychological Science, 2021
openaire   +2 more sources

Mate Choice Copying

Encyclopedia of Evolutionary Psychological Science, 2016
A. Little
openaire   +2 more sources

Mate Choice

Encyclopedia of Personality and Individual Differences, 2020
openaire   +2 more sources

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