Cycloastragenol derivatives regulate the TLR4/NF‐κB/TERT signaling pathway and tyrosine metabolism, breaking the vicious cycle of “inflammation‐aging” and improving symptoms of Parkinson's disease. This study provides direction for the application of natural products in the development of PD drugs.
Shengnan Xiao +5 more
wiley +1 more source
Genome-wide CRISPR screening identifies <i>CLDN1</i> as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer. [PDF]
Wang X +9 more
europepmc +1 more source
The Ecological Mechanism of Coral–Algal Phase Shifts: A Case Study of Wenchang in Hainan Province
This study selected the coral reef areas in the coastal waters of Wenchang, Hainan, China, which were significantly affected by human activities. Through four consecutive years of field investigations, the key driving factors and potential mechanisms of ecological phase shifts between corals and macroalgae were identified, thus providing a scientific ...
Yihua Lyu +6 more
wiley +1 more source
Pro-cognitive efficacy of Prospekta in a rat model of age-associated cognitive impairment. [PDF]
Kardash E +4 more
europepmc +1 more source
Structural insights into antagonist recognition by the vasopressin V2 receptor. [PDF]
Zhang T +17 more
europepmc +1 more source
Special Issue "Natural Products in Drug Discovery and Development". [PDF]
Gao TL.
europepmc +1 more source
Correction: Post-translational modifications in sepsis-induced acute kidney injury: mechanisms and perspectives. [PDF]
Song L +6 more
europepmc +1 more source
Proteomics and acetyl-proteomics reveal the antibacterial mechanism of berberine sulfate against methicillin-resistant Staphylococcus aureus. [PDF]
Hu Z +9 more
europepmc +1 more source

