Results 41 to 50 of about 169,768 (264)

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

La forma como sujeto: ¿un desliz de Aristóteles? Eidos como sujeto y garante de la identidad

open access: yesEstudios de Filosofía, 2013
En este texto argumento a favor de la consideración de la forma (εἶδος) como sujeto y, por tanto, como responsable de la identidad del objeto a través del movimiento.
Claudia Patricia Carbonell Fernández
doaj  

Body/Ciało/Cielesność – o materii w filmach Małgorzaty Szumowskiej

open access: yesKwartalnik Filmowy, 2020
Jednym z głównych tematów powracających w twórczości Małgorzaty Szumowskiej jest ciało ujęte w sposób podmiotowy, jako konstytutywny element tożsamości, oraz przedmiotowy, jako obiekt zabiegów medycznych, fragmentaryzacji, rozkładu, autopsji.
Magdalena Podsiadło-Kwiecień
doaj   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

open access: yesAdvanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng   +12 more
wiley   +1 more source

N‐Doping Activated Presodiation Enhances Sodium‐Ion Provision in Hard Carbon Anodes

open access: yesAdvanced Science, EarlyView.
Introducing pyrrolic‐N sites enables efficient presodiation and stronger PF6− capture, thus pre ‐ forming a robust inorganic‐rich SEI layer in hard carbon anodes. ABSTRACT Hard carbon (HC) is considered the most promising anode material for commercial sodium‐ion batteries (SIBs), yet it still faces critical challenges such as low initial Coulombic ...
Hua Lin   +8 more
wiley   +1 more source

Dall'antropologia filosofica all'ontologia sociale e ritorno: che fare con la sesta tesi di Marx su Feuerbach?

open access: yesNóema, 2015
Il testo che qui presentiamo riproduce un articolo tratto dal volume miscellaneo Il transindividuale. Soggetti, relazioni, mutazioni, a cura di E. Balibar e V. Morfino, Mimesis, Milano 2014, (pp. 147-178).
Etienne Balibar
doaj   +1 more source

THE TEACHING OF MATERIA MI [PDF]

open access: yesAJN, American Journal of Nursing, 1916
n ...
openaire   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

Eliasz nauk. Apokaliptyka, paracelsjańska mistyka przyrody i narodziny nowoczesności

open access: yesPraktyka Teoretyczna, 2016
Mit Eliasza Artysty (albo „Eliasza nauk/sztuk”) jest jednym z interesujących komponentów bogatej szesnastowiecznej tradycji paracelsjańskiej z marginesów poreformacyjnej ortodoksji.
Marek Woszczek
doaj   +1 more source

DOCKʼS MATERIA MEDICA [PDF]

open access: yesAJN, American Journal of Nursing, 1906
n ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy