Results 151 to 160 of about 510,925 (311)

Enhanced thermostability of nattokinase by rational design of disulfide bond

open access: yesMicrobial Cell Factories
Nattokinase, the thrombolytically active substance in the health food natto, nevertheless, its lower thermostability restricts its use in food and pharmaceutical applications.
Kongfang Yu   +8 more
doaj   +1 more source

Glutamine metabolism modulates microglial NLRP3 inflammasome activity through mitophagy in Alzheimer’s disease

open access: yesJournal of Neuroinflammation
The NLR family pyrin domain containing 3 (NLRP3) inflammasome in microglia is intimately linked to the pathogenesis of Alzheimer’s disease (AD). Although NLRP3 inflammasome activity is regulated by cellular metabolism, the underlying mechanism remains ...
Zhixin Zhang   +6 more
doaj   +1 more source

Biliary NF‐κB‐Inducing Kinase Promotes Ductular Reaction, Inflammation, and Fibrosis and Impedes Liver Disease Resolution

open access: yesThe FASEB Journal, Volume 39, Issue 23, 15 December 2025.
Pathogenic factors stimulate biliary NIK, which induces aberrant cholangiocyte expansion and ductular reaction, leading to cholestatic injury. In addition, NIK stimulates secretion of cholangiokines that activate macrophages/Kupffer cells and hepatic stellate cells (HSCs), thereby driving liver inflammation and fibrosis and impairing liver injury ...
Yina Wang   +3 more
wiley   +1 more source

SuperTCM: A biocultural database combining biological pathways and historical linguistic data of Chinese Materia Medica for drug development.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Qiaofeng Chen   +10 more
semanticscholar   +1 more source

Mono-ADP-ribosylation, a MARylationmultifaced modification of protein, DNA and RNA: characterizations, functions and mechanisms

open access: yesCell Death Discovery
The functional alterations of proteins and nucleic acids mainly rely on their modifications. ADP-ribosylation is a NAD+-dependent modification of proteins and, in some cases, of nucleic acids.
Hao Wu   +5 more
doaj   +1 more source

Materia Medica [PDF]

open access: yesPostgraduate Medical Journal, 1956
openaire   +1 more source

La materia mediçinal de la Nueva España: indagaciones sobre su origen e historia [PDF]

open access: yes
El hallazgo de un manuscrito atribuido a Francisco Hernández, la Materia mediçinal de la Nueva España, da pie en este artículo a enunciar una serie de hipótesis sobre su autor, contenido y origen.
Figueroa-saavedra, Miguel
core   +1 more source

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