Results 31 to 40 of about 86,978 (136)

Identifying potential therapeutic targets of mulberry leaf extract for the treatment of type 2 diabetes: a TMT-based quantitative proteomic analysis

BMC Complementary Medicine and Therapies, 2023
Background Mulberry (Morus alba L.) leaf, as a medicinal and food homologous traditional Chinese medicine, has a clear therapeutic effect on type 2 diabetes mellitus (T2DM), yet its underlying mechanisms have not been totally clarified.
Lu Shi, Jingkang Wang, Changhao He, Yan Huang, Wanxin Fu, Huilin Zhang, Yongcheng An, Menglu Wang, Ziyi Shan, Huimin Li, Yinglan Lv, Chen Wang, Long Cheng, Hongyu Dai, Yuhui Duan, Hongbin Zhao, Baosheng Zhao   +16 more
doaj   +1 more source

Comments on Materia Medica [PDF]

The Journal of Nervous and Mental Disease, 1894
n ...
openaire   +1 more source

Lipidomics Indicates the Hepatotoxicity Effects of EtOAc Extract of Rhizoma Paridis

Frontiers in Pharmacology, 2022
Rhizoma Paridis is a traditional Chinese medicine commonly used in the clinical treatment of gynecological diseases. Previous studies have shown that aqueous extracts of Rhizoma Paridis exhibit some hepatotoxicity to hepatocytes.
Chaofeng Li, Mingshuang Wang, Tingting Fu, Zhiqi Li, Yang Chen, Tao He, Dan Feng, Zhaoyi Wang, Qiqi Fan, Meilin Chen, Honggui Zhang, Ruichao Lin, Chongjun Zhao   +12 more
doaj   +1 more source

THE TEACHING OF MATERIA MEDICA [PDF]

AJN, American Journal of Nursing, 1916
n ...
openaire   +1 more source

N‐Doping Activated Presodiation Enhances Sodium‐Ion Provision in Hard Carbon Anodes

Advanced Science, EarlyView.
Introducing pyrrolic‐N sites enables efficient presodiation and stronger PF6− capture, thus pre ‐ forming a robust inorganic‐rich SEI layer in hard carbon anodes. ABSTRACT Hard carbon (HC) is considered the most promising anode material for commercial sodium‐ion batteries (SIBs), yet it still faces critical challenges such as low initial Coulombic ...
Hua Lin, Wenxing Miao, Yanrong Shi, Guangyi Mao, Ding Ding, Jian Weng, Zhongxiong Fan, Qingchi Xu, Jun Xu   +8 more
wiley   +1 more source

An ethnobotanical study on medicinal food plants used by the Kazakh people in Altay, Xinjiang, China

Journal of Ethnobiology and Ethnomedicine
Background The Kazakh people of Altay, Xinjiang, possess rich traditional knowledge associated with medicinal food plants (MFPs), shaped by their nomadic pastoralist heritage and the unique mountain-grassland ecosystems of the region.
Ya-qin Zhao, Bo Lei, Yuan-jin Qiu, Ji-zhao Zhang, Wen-dan Song, Yelxat Danabek, Cong-zhao Fan, Guo-ping Wang   +7 more
doaj   +1 more source

A New Antimalarial Noreudesmane Sesquiterpenoid from Dobinea delavayi

Natural Products and Bioprospecting, 2020
One previously undescribed angeloylated noreudesmane sesquiterpenoid, dobinin O (1), along with four known eudesmane sesquiterpenoids (2–5) were isolated from the peeled roots of Dobinea delavayi.
Xiu-Rong Wu, Yi Shen, Shu-Jun Cui, Xiao-Lei Luo, Chao-Jiang Xiao, Bei Jiang   +5 more
doaj   +1 more source

Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation

Frontiers in Pharmacology, 2022
Shaogan Fuzi Decoction (SGFD), one of the classical prescriptions of Chinese Medicine, has a long history in the treatment of rheumatoid arthritis (RA), but definitive studies on its efficacy and mechanism of action are lacking.
Lu Shi, Yiying Zhao, Chenran Feng, Feng Miao, Linlin Dong, Tianquan Wang, Antony Stalin, Jingyuan Zhang, Jingru Tu, Kexin Liu, Wenyan Sun, Jiarui Wu, Jiarui Wu   +12 more
doaj   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source