Results 151 to 160 of about 8,554,042 (318)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Matemàtiques : geometria A [PDF]

open access: yes, 1990
Este vídeo trata sobre geometría. Forma parte de la colección de material autoformativo de las asignaturas de matemáticas, conocimiento del medio natural y educación visual y plástica, musical y corporal ...

core  

The Societal Nature of Subjectivity: An Interdisciplinary Methodological Challenge

open access: yesForum: Qualitative Social Research, 2012
The thematic issue presents a psycho-societal approach to qualitative empirical research in several areas of everyday social life. It is an approach which integrates a theory of subjectivity and an interpretation methodology which integrates hermeneutic ...
Henning Salling Olesen
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

­Hola escuela! : materiales para la enseñanza de español, lengua extranjera, a inmigrantes [PDF]

open access: yes, 2007
Material de apoyo al profesor en la enseñanza del español como lengua extranjera al alumnado inmigrante. Consta de una parte teórica sobre educación intercultural y enseñanza de las lenguas extranjeras y una unidad didáctica para el alumnado de segundo y
Muñoz López, María Belén   +8 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The biophysical perspective of a middle income economy: Material Flows in Mexico [PDF]

open access: yes
We analyse natural resource use dynamics in the Mexican economy during the last three decades. Despite low and uneven economic growth, the extraction and use of materials in the Mexican economy has continuously increased during the last 30 years. In this
Ana Citlalic Gonzalez-Martinez   +1 more
core   +3 more sources

Optimizing hybrid fiber concrete: an experimental analysis of steel and polypropylene fiber composites using RSM

open access: yesMaterials Research Express
Concrete inherent brittleness, limits its performance under various loading conditions, posing challenges in high-performance applications. Hybrid fiber-reinforced concrete (HYFRC), incorporating both steel and polypropylene fibers, has emerged as a ...
Muhammad Aftab Khan   +1 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Matemàtiques : probabilitat i estadística [PDF]

open access: yes, 1990
Este vídeo trata sobre probabilidad y estadística. Forma parte de la colección de material autoformativo de las asignaturas de matemáticas, conocimiento del medio natural y educación visual y plástica, musical y corporal ...

core  

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