Results 81 to 90 of about 2,266,284 (314)

Relational Identities and Other-Than-Human Agency in Archaeology

, 2018
Relational Identities and Other-than-Human Agency in Archaeology explores the benefits and consequences of archaeological theorizing on and interpretation of the social agency of nonhumans as relational beings capable of producing change in the world ...
Harrison-Buck, Eleanor, Hendon, Julia A.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Experiencing space–time: the stretched lifeworlds of migrant workers in India [PDF]

, 2012
In the relatively rare instances when the spatialities of temporary migrant work, workers’ journeys, and labour-market negotiations have been the subject of scholarly attention, there has been little work that integrates time into the analysis.
Bag K, Breman J, Chari S, Deshingkar P, Dicken P, Harriss-White B, Harvey D, Harvey D, Khasnabis R, Massey Deeptima, Massey Deeptima, Massey Doreen, Mitchell D, Rafique A, Rafique A, Rafique A, Raju S, Raju S, Raju S, Rogaly B, Rogaly B, Rogaly B, Rolshoven J, Roy A, Schier M, Standing G, Thieme S, Thieme S, Thieme S, Waite L, Watts S   +30 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

After Affects [PDF]

, 2018
Young people of color face considerable obstacles to racial, educational, economic, and social equity, yet the remedies to these problems rarely involve attention to the insights and experiences of youth themselves.
Bucholtz, Mary, Casillas, Dolores Inés, Lee, Jin Sook   +2 more
core   +4 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Mechanical Properties of Recycling Mixed Waste Plastic Predicted on Pallet Application Using Finite Element Analysis [PDF]

E3S Web of Conferences
The enormous use of plastic in any live sector will impact the waste plastic escalation. Unsorted and uncollected wasted plastic properly leads to the creation of mixed waste plastic in landfills. Therefore, mechanical recycling technology for processing
Taqwatomo Galih, Novriadi Dwi, Marsaputra Panjaitan Boy, Prasetyo Hariaman, Subagyo Yusuf, Eka Mulyono Aditya, Rahayu Sri, Kusuma Arti Dewi, Pradipta Arjasa Putra Oka   +8 more
doaj   +1 more source

Enforcing the Bargain v. Materiality Requirement: The Future of Disclosure-Only Settlements Post-Trulia [PDF]

, 2018
In In re Trulia, Inc. Stockholder Litigation, the Delaware Court of Chancery broke away from its tradition of routinely approving disclosure-only settlements and required disclosures to be material in order to cure the conflict of interest between ...
Jiang, Hao
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

DIFFERENTIAL PULSE ANODIC STRIPPING VOLTAMMETRY FOR DETERMINATION OF SOME HEAVY METALS IN URANIUM

Indonesian Journal of Chemistry, 2010
The direct determination of some metals impurity in uranium by using differential pulse anodic stripping voltammetry (DPASV) method at a hanging mercury drop electrode and in a carbonate buffer media was developed.
Saryati Saryati
doaj   +1 more source