Results 101 to 110 of about 3,304,310 (344)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Mathematical Model of Drilling Mud Movement along a Shale Shaker Screen

Advanced Engineering Research
Introduction. When drilling oil or gas wells, rock from the bottomhole is brought to the surface by drilling mud, which is cleaned of sludge by shale shakers at the first stage.
I. Yu. Kichkar
doaj   +1 more source

PENGUKURAN KOEFISIEN AERODINAMIS MODEL-MODEL JEMBATAN BENTANG PANJANG [PDF]

, 2013
The objective of this research is to measure aerodynamic coefficients of long-span bridge deck models. Four models with different wind nose (fairings) will be tested using open loop wind tunnel.
Sangadji, Senot
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Improvement of Mass Transfer Characteristics for the Gas-Liquid System in a Vortex Counterflow Apparatus

Energies
This article aims to increase the intensity of mass transfer between gas and liquid in counterflow gas–liquid flow, one of the key problems in designing mass transfer equipment.
Vsevolod Sklabinskyi, Ivan Pavlenko, Maksym Skydanenko, Sylwia Włodarczak, Andżelika Krupińska, Marek Ochowiak, Izabela Kruszelnicka   +6 more
doaj   +1 more source

SELECTION OF LIPIDS FROM BLUE-GREEN ALGAE [PDF]

, 2018
Annually Ukraine consumes about 200 million tons of fuel oil equivalent, however, the mining from country’s natural resources is only 80 million tons.
Chelnakova, Olena, Detsyura, Karina, Kozlovska, Tetyana, Novokhatko, Olha   +3 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The use of mathematical model to evaluate the material balance of a solid oxide electrolyser

Омский научный вестник
The effective use of solid oxide electrolysers is a promising solution for the energy sector and industry in general. Therefore, scientists all over the world are conducting research on improving the electrolysers' efficiency and reliability.
A. I. Golodnova, M. V. Erpalov, A. I. Golodnov   +2 more
doaj   +1 more source

A Simple Approach to Dynamic Material Balance in Gas-Condensate Reservoirs

Oil & Gas Science and Technology, 2013
In traditional material balance calculations, shut-in well pressure data are used to determine average reservoir pressure while recent techniques do not require the well to be shut-in and use instead flowing well pressure-rate data ...
Heidari Sureshjani M., Gerami S., Emadi M.A.   +2 more
doaj   +1 more source