Results 191 to 200 of about 1,055,110 (303)

Computational modeling for PPE filtration: Informed by material characterization, microbial penetration, and particle mechanics. [PDF]

open access: yesJ Occup Environ Hyg
Kastor W   +12 more
europepmc   +1 more source

A Review on Mechanical Models for Cellular Media: Investigation on Material Characterization and Numerical Simulation. [PDF]

open access: yesPolymers (Basel), 2021
Luo G   +10 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Vibroacoustic signatures: proof of concept for simple material characterization during needle interventions. [PDF]

open access: yesInt J Comput Assist Radiol Surg
Steeg K   +7 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Scalable Synthesis of Hide Substance–Chitosan–Hydroxyapatite: Novel Biocomposite from Industrial Wastes and Its Efficiency in Dye Removal

open access: yesACS Omega, 2018
Sandipan Chatterjee   +8 more
doaj   +1 more source

Vacuum Based Gas Sensing Material Characterization System for Precise and Simultaneous Measurement of Optical and Electrical Responses. [PDF]

open access: yesSensors (Basel), 2022
Wei J   +15 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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