Results 91 to 100 of about 825,836 (312)

Special Libraries, June 1917 [PDF]

, 1917
Volume 8, Issue 6https://scholarworks.sjsu.edu/sla_sl_1917/1005/thumbnail ...
Special Libraries Association
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Mongolia Country Profile [PDF]

, 2003
[From Introduction] This country study for Mongolia is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation\u27 which aims to enhance the capacity of national governments in selected countries of Asia and East ...
Infocus Programme on Skills, Knowledge and Employability/Disability Programme, International Labour Office   +1 more
core   +1 more source

Archaeology and autonomies: the legal framework of heritage management in a new Bolivia [PDF]

, 2011
The 2009 Bolivian Constitution significantly changed the structure of the state and paved the way for the creation of regional, local, and even indigenous autonomies.
Dangl, Donna Yates, Gasparini, Kohl, Mamani Condori, Ponce Sanginés, Rivera Cusicanqui   +6 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Path dependence and political bargaining in the elaboration of contents of authoritarian constitutions: the Portuguese Constitution of 1933

European Law Open
This article examines the process of drafting the authoritarian Portuguese Constitution of 1933, which took place during the military regime. The aim is to identify the powers involved, their objectives and the strategies they developed, and to find ...
Paula Borges Santos
doaj   +1 more source

Methodological considerations on the new relationship between State, Law and Social Justice within the European market constitutionalism

Estudios de Deusto, 2014
In recent years the novelties included by the European legal system have introduced a scenario of reflection with regard to the Social state constitutionalism.
Ainhoa Lasa López
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The biomechanical effects of different membrane layer structures and material constitutive modeling on patient-specific cerebral aneurysms

Frontiers in Bioengineering and Biotechnology
The prevention, control and treatment of cerebral aneurysm (CA) has become a common concern of human society, and by simulating the biomechanical environment of CA using finite element analysis (FEA), the risk of aneurysm rupture can be predicted and ...
Xuanze Fan, Aohua Zhang, Qingli Zheng, Pengcui Li, Yanqin Wang, Liming He, Yanru Xue, Yanru Xue, Weiyi Chen, Xiaogang Wu, Xiaogang Wu, Yongwang Zhao, Yonghong Wang   +12 more
doaj   +1 more source