Results 71 to 80 of about 825,836 (312)

Bodies, technologies and action possibilities: when is an affordance? [PDF]

, 2010
Borrowed from ecological psychology, the concept of affordances is often said to offer the social study of technology a means of re-framing the question of what is, and what is not, ‘social’ about technological artefacts. The concept, many argue, enables
Akrich, M., Asch, S., Barad, K., Brian P. Bloomfield, Dahrendorf, R., Derrida, J., Dohn, N., Fairclough, N., Fayard, A.-L., Gibson, J., Grint, K., Hutchby, I., Kaku, M., Kranz, G., Latour, B., Law, J., Lovell, J., McGrenere, J., Michael, M., Michaels, C., Moser, I., Mumford, L., Scarry, E., Stork, D., Theo Vurdubakis, Winance, M., Yvonne Latham   +26 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

JUDICIAL REVIEW SEBAGAI SARANA PERLINDUNGAN HAK-HAK ASASI WARGA NEGARA

DiH, 2015
Observing the development of public acceptance of the substance of the laws that were generated in recent time, the right of judicial review of an option that can not be avoided for the 'correct' errors that might occur in a legal product to guarantee ...
Safi’ Safi’
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Propotions of total body sizes and organometrical parameters of heart and aorta of adult men [PDF]

Саратовский научно-медицинский журнал, 2013
Purpose: To study correlation of total body sizes, heart and aorta at adult men. Material and Methods: Heart and aorta organometry has been carried out at 80 corpses of adult men (31-70 years) with known anthropometrical parameters with the subsequent ...
Chelnokova N.O., Ostrovsky N.V., Anisimova Е.А., Murylev V.V.   +3 more
doaj  

Exploration of the High Entropy Alloy Space as a Constraint Satisfaction Problem [PDF]

, 2017
High Entropy Alloys (HEAs), Multi-principal Component Alloys (MCA), or Compositionally Complex Alloys (CCAs) are alloys that contain multiple principal alloying elements. While many HEAs have been shown to have unique properties, their discovery has been
Abu-Odeh, Anas, Arroyave, Raymundo, Chen, Qing, Galvan, Edgar, Kirk, Tanner, Malak, Richard, Mao, Huahai, Mason, Paul   +7 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

OVERALL ASSESSMENT OF PHYSICAL FITNESS IN CHILDREN WITH MENTAL RETARDATION IN THE TEST "EUROFIT SPECIAL"

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013
Purpose. The aim of this research was to assess general extensive physical efficiency in children suffering from moderate mental disability with the use of “Eurofit Special” tests, and to compare general extensive physical efficiency and its components ...
Bartosz Bolach, Tetyana Pystupa
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A study to characterize the mechanical properties and material constitution of adult descending thoracic aorta based on uniaxial tensile test and digital image correlation. [PDF]

Front Bioeng Biotechnol, 2023
Li Z, Pei M, Zhang J, Liu N, Wang J, Zou D.   +5 more
europepmc   +1 more source