Results 81 to 90 of about 825,836 (312)
Preparing the Way: Tom Stewart’s Recollections On the Alaska State Constitutional Convention [PDF]
, 2018 One of the most important figures in the successful effort for Alaska statehood was Tom Stewart. Born into an established Juneau family headed by Ben Stewart, founder of the Alaska Territorial Department of Mines, Tom was raised in Juneau.
Metzloff, Thomas
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
LEGAL OBLIGATION IN THE CONSTITUTION
Вестник Кемеровского государственного университета, 2015 This study examines legal responsibilities in the constitution. Legal obligation is the key category of any branch of law. Legal duties of constitutional nature are of particular socio-legal significance, given the fundamental nature of the provisions of
V. P. Shchennikov, N. V. Antsiferov
doaj
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Constitution and the Falling Elevator: The Continuing Incompatibility of Materialism and Resurrection Belief [PDF]
Ontological dualism is energetically resisted by a range of Christian scholars including philosophers such as Baker and Corcoran who defend accounts of human persons based on material constitution.
Loose, Jonathan J.
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Computer Modeling of Personal Autonomy and Legal Equilibrium
, 2018 Empirical studies of personal autonomy as state and status of individual freedom, security, and capacity to control own life, particularly by independent legal reasoning, are need dependable models and methods of precise computation.
H Ashrafian +3 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Materializing policies for sustainable use and economy-wide management of resources: biophysical perspectives, socio-economic options and a dual approach for the European Union [PDF]
Policies for Sustainable Use and economy-wide Management of natural Resources (SUMR) throughout the production and consumption system are faced with environmental and socio-economic requirements and regulatory constraints.
Bringezu, Stefan
core