Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Faster differentiation of Staphylococcus aureus versus coagulase-negative Staphylococci from blood culture material: a comparison of different bacterial DNA isolation methods [PDF]
, 2009 A.J.M. Loonen +6 more
openalex +1 more source
La perspectiva intercultural en los libros para la enseñanza de lenguas modernas.Un enfoque histórico [PDF]
, 2006 This paper analyses the pedagogical and practical approaches to the teaching of culture which were used in a range of popular French, Spanish, Italian and German grammars and text-books published in the XIX century in Europe and America.
Gallardo, Matilde
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Friables and embryogenic callus induction from embryo, ovule and style of citrus rootstocks : [P97] [PDF]
, 2008 The incorporation of new technologies such as in vitro selection and protoplast fusion methods into citrus improvement programs offers new opportunities to facilitate, expedite, and fully utilize germplasm variability for both scion and rootstock ...
Arsalan, N. +6 more
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
TEACHING MATERIALS ON THE HISTORY AND CULTURE OF ISLAM: THE LATEST ISSUES REVIEW
, 2016 Oleg Redkin, Olga Bernikova
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
"Living in a Material World: Material Culture and Historical Inquiry"
, 2013 Sandra Aubé
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source