Results 171 to 180 of about 3,285,334 (317)
Australia some of the main developmental projects [cartographic material] /
, 1950 Map of Australia showing major building projects.; "Ref no. AI02/16-1-Oct.
Australia. Department of National Development.
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Kisumu East District Development Plan 2002-2008
, 2002 The 8th District Development Plan (DDP) for the period 2008-2012 was prepared by the District Planning and Monitoring Unit in close collaboration with members of the various Sector Working Groups (SWGs).
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Rachuonyo District Development Plan 2008-2012
, 2009 The 8th District Development Plan (DDP) for the period 2008-2012 was prepared by the District Planning and Monitoring Unit in close collaboration with members· of the various Sector Working Groups (SWGs).
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Vihiga District Development Plan 2008-2012
, 2009 The 8th District Development Plan (DDP) for the period 2008-2012 was prepared by the District Planning and Monitoring Unit in close collaboration with members of the various Sector Working Groups (SWGs).
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Trans Nzoia West District Development Plan 2008-2012
, 2008 The 8th District Development Plan (DDP) for the period 2008-2012 was prepared by the District Planning and Monitoring Unit in close collaboration with members of the various Sector Working Groups (SWGs).
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source