Results 211 to 220 of about 16,620,600 (346)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Investments in material efficiency: the introduction and application of a comprehensive cost–benefit framework

, 2017
F. Flachenecker, R. Bleischwitz, Jun Rentschler   +2 more
semanticscholar   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Study on the Efficiency and Mechanism of a Novel Copper-Based Composite Material Activated by Supramolecular Self-Assembly for Degrading Reactive Red 3BS. [PDF]

Nanomaterials (Basel)
Dai J, Wang X, Chen B, Chen L.
europepmc   +1 more source

The Role of Material Efficiency in Environmental Stewardship

, 2016
E. Worrell, J. Allwood, T. Gutowski
semanticscholar   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Sustainable design of organic solar cells utilized machine and deep learning. [PDF]

Sci Rep
Mohyeldien OM, El-Amary NH, Al Bardawil A.   +2 more
europepmc   +1 more source

Energy and material efficiency metrics in foundries

, 2018
Emanuele Pagone, K. Salonitis, M. Jolly
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Effect of porous material and black coating on solar desalination for sustainable water harvesting: A thermo-exergo-economic and environmental analysis. [PDF]

Sci Rep
Sharma N, Kumar A, Cep R, Monika, Katiyar A.   +4 more
europepmc   +1 more source