Results 51 to 60 of about 1,041,279 (261)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Criteria in Utilizing Engineered Wood in Residential Construction

Dimensi: Journal of Architecture and Built Environment
The phenomenon of global warming continues to intensify, with the construction sector emerging as a significant contributor due to its extensive use of non-biomass materials, which are major sources of carbon emissions.
Eryonata Melino, Dewi Larasati, Hanson E Kusuma   +2 more
doaj   +1 more source

Diagnostics Experience of Comprehensive School Pupils’ Meta-subject Competences (on the Mathematic Material)

Психологическая наука и образование (2007. Online), 2017
introduction of the new educational standards of fundamental general education. The experiment of diagnostics implementation of competences among 5-6th graders aged 10-15 is being observed. Tasks instances are presented, particularly of the ones based on
Sokolov V.L.,, Fomin A.A.,
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Design and Development of an Edugame Arabic for Learning Media

IJID (International Journal on Informatics for Development)
Learning media provides significant advantages to students by improving their learning experience through the use of multimedia applications, resulting in a more engaging and fascinating learning environment while reducing the monotony associated with ...
Yudha Riwanto, Inggrid Yanuar Risca Pratiwi, Asri Wulan Septiana, Fauzia Anis Sekar Ningrum, Ajie Kusuma Wardhana   +4 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

SET-based experiments for HTSC materials [PDF]

Superconductor Science and Technology, 2002
The cuprates seem to exhibit statistics, dimensionality and phase transitions in novel ways. The nature of excitations [i.e. quasiparticle or collective], spin-charge separation, stripes [static and dynamics], inhomogeneities, psuedogap, effect of impurity dopings [e.g. Zn, Ni] and any other phenomenon in these materials must be consistently understood.
Alam, Sher, Rahman, M. O., Yanagisawa, T., Oyanagi, H.   +3 more
openaire   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Materiell og profesjonell stigmatisering av mennesker med sykelig overvekt

Nordisk Tidsskrift for Helseforskning, 2017
The aim of this study is to show how people suffering from severe obesity might experience stigmatization. We interviewed 6 persons recruited from a Norwegian rehabilitation center, specialized in lifestyle intervention in severe obesity.
Wenche Skeivoll Christiansen, Tor-Ivar Karlsen, Inger Beate Larsen   +2 more
doaj   +1 more source