Results 141 to 150 of about 6,819,857 (275)

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

Warpage in Material Extrusion Additive Manufacturing of Amorphous and Semicrystalline Polymers

open access: yesMacromolecular Materials and Engineering
Material Extrusion Additive Manufacturing (MEAM) offers the ability to manufacture complex geometries through layer‐by‐layer deposition. MEAM involves fast heating and cooling of polymers, processes that involve thermal expansion and contraction of ...
Ali Zerriouh   +7 more
doaj   +1 more source

Machine learning enabled 3D printing parameter settings for desired mechanical properties

open access: yesVirtual and Physical Prototyping
Additive manufacturing facilitates the production of parts with tailored mechanical properties, yet achieving specific stress–strain responses remains a significant challenge due to the intricate relationship between printing parameters and material ...
Linlin Wang   +5 more
doaj   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Thermomechanical Response of Polycarbonate/Aluminum Nitride Nanocomposites in Material Extrusion Additive Manufacturing. [PDF]

open access: yesMaterials (Basel), 2022
Vidakis N   +7 more
europepmc   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

open access: yesAdvanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li   +9 more
wiley   +1 more source

Optimising 3D-printed flexible lattice structures for morphing applications by linking rheology to mechanical behaviour

open access: yesVirtual and Physical Prototyping
Additive manufacturing, particularly extrusion-based additive manufacturing (EB-AM), has transformed the fabrication of complex structures. Thermoplastic Polyurethane (TPU), valued for its elasticity and durability, is an ideal material for flexible ...
Laia Farràs-Tasias   +4 more
doaj   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti   +10 more
wiley   +1 more source

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