Results 161 to 170 of about 9,803,493 (256)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Study on Material Flow Behavior in Three-Dimensional Directions During Friction Stir Welding and the Establishment of a Qualitative Model. [PDF]

Materials (Basel)
Wei CG, Lu S, Chen J, Zhang J, Zhu JL, Gridasov AV, Statsenko VN, Pogodaev AV.   +7 more
europepmc   +1 more source

Standardized method for material flow data collection at city level. [PDF]

Data Brief, 2021
Gao H, Tian X, Zhang Y, Shi L, Shi F.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Opportunities to reduce the environmental impact of endoscopy: a detailed material flow analysis of diagnostic colonoscopy. [PDF]

Endoscopy
Izci CB, Clercx Lao MS, Vegting B, Siersema PD, Tietschert MV, Hunfield NGM, Diehl JC, de Jonge PJF.   +7 more
europepmc   +1 more source

Fate identification and management strategies of non-recyclable plastic waste through the integration of material flow analysis and leakage hotspot modeling. [PDF]

Sci Rep, 2022
Rinasti AN, Ibrahim IF, Gunasekara K, Koottatep T, Winijkul E.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Mapping mismanaged plastic waste in Indonesia: subdistrict-level analysis through material flow from sources to the environment. [PDF]

Sci Rep
Ramadan AH, Sembiring E, Rahardyan B, Kardhana H.   +3 more
europepmc   +1 more source

Material flow analysis and characteristics of multiple-source organic solid wastes from a perspective of ecological network analysis: A case study in Hefei, China. [PDF]

Waste Manag Res, 2023
Zhang Y, Zhou C, Du J, Wang M, Wu W, Liu G.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source