Results 101 to 110 of about 3,808,670 (254)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Material Properties Measurements for Selected Materials [PDF]

open access: yes
Hugoniot equation of state measurements were made on Coconino sandstone, Vacaville basalt, Kaibab limestone, Mono Crater, pumice and Zelux (a polycarbonate resin) for pressures to 2 Mb. A single data point was obtained for fused quartz at 1.6 Mb.
Green, S. J.   +5 more
core   +1 more source

Finite element analysis of compressible solids with nonlinear material properties [PDF]

open access: yes, 1969
Finite-element computer program solves for nodal point displacements in an axisymmetric solid. The options in the program include plane stress analysis, axisymmetric solids analysis, nonlinear /plastic/ analysis, and equivalent stress and ...
Wilson, E. L.
core   +1 more source

Transport properties of Layer-Antiferromagnet CuCrS2: A possible thermoelectric material

open access: yes, 2010
The electrical, thermal conductivity and Seebeck coefficient of the quenched, annealed and slowly cooled phases of the layer compound CuCrS2 have been reported between 15K to 300K.
A. K. Rastogi   +15 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Mechanical properties of a porous mullite material [PDF]

open access: yes
Modulus of rupture specimens were used to determine crack growth parameters of a porous mullite material. Strength testing was performed in ambient and moist environments.
Viens, Michael J.
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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