Results 111 to 120 of about 5,369,316 (340)

Additively Produced Ti-6Al-4V Osteosynthesis Devices Meet the Requirements for Tensile Strength and Fatigue

Journal of Manufacturing and Materials Processing
The purpose of this study was to estimate the peak stresses in a laser powder bed fusion (LPBF) additive-manufactured (AM) osteosynthesis plate during physiological loading and establish if the mechanical properties of LPBF titanium alloy were suitable ...
Alisdair R. MacLeod, Matthew Bishop, Alberto Casonato Longo, Alborz Shokrani, Chris Rhys Bowen, Harinderjit Singh Gill   +5 more
doaj   +1 more source

Transport properties of Layer-Antiferromagnet CuCrS2: A possible thermoelectric material

, 2010
The electrical, thermal conductivity and Seebeck coefficient of the quenched, annealed and slowly cooled phases of the layer compound CuCrS2 have been reported between 15K to 300K.
A. K. Rastogi, CDW Jones, FJ Blatt, FK Lotgering, FMR Engelsman, Girish C. Tewari, GM Abramova, H Kawaji, J Dijkstra, M Wintenberger, MA Boutbila, N Le Nagard, PF Bongers, RP Van Stapele, T. S. Tripathi, W Bronger   +15 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A 3D FEM-Based Numerical Analysis of the Sheet Metal Strip Flowing Through Drawbead Simulator

Metals, 2019
Drawbeads are elements of the stamping die and they are used to compensate material flow resistance around the perimeter of the drawpiece or to change the stress state in specific regions of the drawpiece.
Tomasz Trzepiecinski, Romuald Fejkiel
doaj   +1 more source

Supplementary Material for: Complex Material Properties of Gel-Amin: A Transparent and Ionically Conductive Hydrogel for Neural Tissue Engineering

, 2022
Neuman K.E., Alex Kenny, Lei Shi, Koppes A.N., Koppes R.A.   +4 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Techniques for improving computational speed in numerical simulation of casting thermal stress based on finite difference method [PDF]

China Foundry, 2013
Finite difference method (FDM) was applied to simulate thermal stress recently, which normally needs a long computational time and big computer storage.
Xue Xiang, Wang Yueping
doaj  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source