A generalised deep learning-based surrogate model for homogenisation utilising material property encoding and physics-based bounds. [PDF]
Sci Rep, 2023 Nakka R, Harursampath D, Ponnusami SA.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A general-purpose material property data extraction pipeline from large polymer corpora using natural language processing. [PDF]
NPJ Comput Mater, 2023 Shetty P +7 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Biosurface and BiotribologyTitanium (Ti) dental scaffolds are widely used in dental prosthetics due to their excellent mechanical properties and biocompatibility. However, conventional Ti scaffolds manufactured through machining often do not fit perfectly with the bone defect site.
Changfu Lu +6 more
doaj +1 more source
Research of Property and Defect of Fast Reactor MOX Fuel Green Pellet in Floating Pressing
Yuanzineng kexue jishuGreen pellet pressing is critical step in the preparation of oxide ceramic fuel that decides density, strength and microstructure of green pellets and pellets. The medium mode floating pressing properties of calcined alumina and Comeo alumina powder were
ZHANG Han, WANG Junping, ZHU Tongyu, ZHANG Shunxiao, PAN Chuanlong, AI Lijun
doaj +1 more source
Material property alterations for phenotypes of heart failure with preserved ejection fraction: A numerical study of subject-specific porcine models. [PDF]
Front Bioeng Biotechnol, 2022 Weissmann J +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Evaluation of a low-density polyimide foam in a dynamic, high temperature environment [PDF]
A low density polyimide foam material was tested in an arc tunnel to determine its potential for heat shield application on aerospace vehicles. The results show that the material has some reuse potential at surface temperatures as high as 750 K.
Brown, R. D., Pittman, C. M.
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source