Results 41 to 50 of about 588,268 (266)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The effects of austenitization temperature on the microstructural characteristics and mechanical properties of Cr–Mo–V hot work tool steels with different nitrogen contents

Journal of Materials Research and Technology
Two kinds of Cr–Mo–V hot work tool steels with different nitrogen contents, i.e. High-N steel and Low-N steel, were heat treated to investigate phase transformation phenomena in the present study. Microstructure characterization revealed the existence of
Chih-Yuan Chen, Iting Chiang, Yung-Chang Kang   +2 more
doaj   +1 more source

Material properties of titanium diboride

Journal of Research of the National Institute of Standards and Technology, 2000
The physical, mechanical, and thermal properties of polycrystalline TiB2 are examined with an emphasis on the significant dependence of the properties on the density and grain size of the material specimens. Using trend analysis, property relations, and interpolation methods, a coherent set of trend values for the properties of polycrystalline TiB2 is ...
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The effect of retained austenite on austenite reversion behavior and corresponding mechanical properties of Ti–Mo precipitation hardening stainless steels

Journal of Materials Research and Technology
Although the ageing process is the most important metallurgical process influencing the austenite reversion reaction, the role of retained austenite existing after cryogenic treatment on austenite reversion transformation is still not fully explored ...
Chih-Yuan Chen, Iting Chiang, Yung-Chang Kang   +2 more
doaj   +1 more source

Gamma irradiation effects in optical fibres, splitters, and connectors [PDF]

Nuclear Technology and Radiation Protection, 2017
The paper presents a brief overview of contemporary ELION techniques with stress on their use for material modification and dosimetry. In the attempt to avoid some common misjudges of irradiation effects, special attention is paid to exact ...
Srećković Milesa Ž., Pantelić Slađana N., Stanković Srboljub J., Polić Suzana R., Ivanović Nenad B., Bugarinović Aleksandar R., Ostojić Stanko M.   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Coupled effects of nitrogen content and austenitizing temperature on the hardness-toughness balance of Cr–Mo–V hot-work tool steels

Journal of Materials Research and Technology
Nitrogen is widely regarded as beneficial for the hardness–toughness balance of Cr–Mo–V hot-work tool steels, yet retaining high nitrogen during steelmaking is costly and not always feasible.
Jing-Chun Yang, Chih-Yuan Chen, Yung-Chang Kang   +2 more
doaj   +1 more source

Thermoelectric Flexible Silver Selenide Films: Compositional and Length Optimization

iScience, 2020
Summary: Silver selenide is considered as a promising room temperature thermoelectric material due to its excellent performance and high abundance. However, the silver selenide-based flexible film is still behind in thermoelectric performance compared ...
Jie Gao, Lei Miao, Huajun Lai, Sijing Zhu, Ying Peng, Xiaoyang Wang, Kunihito Koumoto, Huanfu Cai   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source