Results 91 to 100 of about 268,551 (262)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Study on electrochemical mechanical polishing of silicon carbide substrates with controllable material removal behavior

Journal of Materials Research and Technology
Electrochemical mechanical polishing (ECMP) shows great potential for improving the polishing efficiency and surface quality of silicon carbide (SiC) substrates.
Qiufa Luo, Dianlong Lin, Yongkang Xin, Jing Lu, Congming Ke, Jianhui Zhu, Hui Huang   +6 more
doaj   +1 more source

Evaluation of ElectrochemicalTreatment in Degradation of Wastewater Contaminated by Propylene Glycol [PDF]

سلامت و محیط, 2010
"n "nBackgrounds and Objectives:Propylene glycol is applied in many industries as raw material and can be released to the environment through wastewater of such industries.
M.R Talaiekhozani, A.R Talaiekhozani, N Jaafarzadeh Haghighi fard, S Jorfi   +3 more
doaj  

Pyrophillite “Parsovići” – Efficient Material in Heavy Metal Removal

, 2019
The present work explored the effectiveness of Parsovići pyrophyllite ore as sorbent material for heavy metals such as Pb, Cu, Zn, Cd and Ni from aqueous solution. The analysis of chemical composition of PIR samples revealed the presence of silica and alumina besides Ca bearing phase; along with FTIR analysis which confirmed presence of hydroxyl groups
Janićijević, Aleksandra, Andrić, Ljubiša, Radulović, Dragan, Milojković, Jelena, Šoštarić, Tatjana, Harbinja, Muhamed, Lopičić, Zorica   +6 more
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Modified CMK-3 carbon materials for efficient removal of roxarsone

Applied Surface Science
Roxarsone adsorption from water using ordered mesoporous carbon CMK-3 (P_CMK-3) and CMK-3 carbon modified with thiourea (TU_CMK-3) or diclofenac (SD_CMK-3) was studied. The adsorption of roxarsone occurred at low pH. The adsorption was fast; in the case of SD_CMK-3 and TU_CMK-3 materials, the adsorption equilibrium was achieved within 2 min, whereas in
Joanna Dobrzyńska, Kinga Morlo, Rafał Olchowski, Ryszard Jan Dobrowolski   +3 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Research on the relationship between acoustic emission signal and material removal rate during fixed abrasive lapping

Jin'gangshi yu moliao moju gongcheng, 2017
Due to passivation and wear, fixed abrasive lapping pad needs to be conditioned.Material removal rate is one of the characteristic indexes to judge the condition of the lapping pad.The relationship between acoustic emission signal and material removal ...
TONG Haocheng, LI Jun, GUO Taiyu, MING Shun, ZHU Yongwei, ZUO Dunwen   +5 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source