Results 201 to 210 of about 18,983,868 (378)

Application of the thermodynamic extremal principle to modeling of thermodynamic processes in material sciences

, 2005
J. Svoboda, I. Turek, F. Fischer
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Correction: Huang et al. Long Non-Coding RNA <i>74687</i> Regulates Meiotic Progression and Gonadal Development in Rainbow Trout (<i>Oncorhynchus mykiss</i>) via the miR-15a-5p-<i>ccne1</i> Regulatory Axis. <i>Int. J. Mol. Sci.</i> 2025, <i>26</i>, 8036. [PDF]

Int J Mol Sci
Huang T, Cao B, Liu E, Gu W, Sun Y, Ge K, Wang G, Li D, Fan P, Xing R, Xu G.   +10 more
europepmc   +1 more source

The material footprint of nations

Proceedings of the National Academy of Sciences of the United States of America, 2013
T. Wiedmann, H. Schandl, M. Lenzen, D. Moran, S. Suh, J. West, Keiichiro Kanemoto   +6 more
semanticscholar   +1 more source

Development of Teaching Materials for Project-Based Physical Education Learning Strategies at the Faculty of Sports Science, Medan State University [PDF]

Ade Ros Riza, Denni Rahman Marpaung, Filli Azandi, Ibrahim Ibrahim   +3 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Fatigue crack growth of glass fiber laminates polymer composites using vacuum bagging technique. [PDF]

PLoS One
Chaloob MK, Laftah RM, Young D, Alwattar TA.   +3 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Correction: Evaluating the sustainability and productivity of conventional, organic, and regenerative agriculture in maize-soybean rotations: a modelling LCA study. [PDF]

Sci Rep
Cavallito A, Bianchi I, Mancia T, Catania D, Rossi M, Marchetti B.   +5 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source