Results 291 to 300 of about 18,983,868 (378)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Climate-driven decline of Norway spruce in Central Europe: a threshold crossing in the warming Carpathian Basin. [PDF]

Int J Biometeorol
Lisztes-Szabó Z, Tóth A, Filep AF, Szentes O, László E, Braun M.   +5 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Vitamin B6 (Pyridoxal 5' Phosphate) antagonises carotid body P2X3 receptors in hypertension. [PDF]

Cardiovasc Res
Felippe ISA, Babbage TL, Shaheen R, Bassetto M, Fan JL, Pauza A, Gold O, Thakkar P, Dawes M, Bates ML, McBryde F, Fountain SJ, Fisher JP, Paton JFR.   +13 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Effect of Crown to Titanium Base Ratio and Force Angle on the Biomechanical Behavior of Dental Implants With CAD/CAM Zirconia and Lithium Disilicate Crowns: A Finite Element Analysis. [PDF]

Clin Exp Dent Res
Abtahi S, Mirzaboland S, Geramy A, Alikhasi M, Siadat H.   +4 more
europepmc   +1 more source

Are iris masses in lung carcinoma always a metastasis: Two case reports. [PDF]

World J Methodol
Nayak B, Mohapatra PR, Chakraborty K, Nanda J, Haripriya S, Mantha SP, Sethy M, Panda BB.   +7 more
europepmc   +1 more source

Material Science Introduction

, 2006
openaire   +2 more sources

Evaluation of an angio-osseo inductive bone ceramic versus demineralised freeze-dried bone allograft in the treatment of periodontal intrabony defects: a randomised controlled clinical trial. [PDF]

Biomater Investig Dent
Sagar S V, Roopavath UK, Sattar N, Babu P R, Nandini AD, Kumari N, Rath SN.   +6 more
europepmc   +1 more source