Results 71 to 80 of about 1,863,396 (264)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Los materiales como medio para estimular procesos de creación

Dearq, 2011
Los materiales deben entenderse desde el diseño y la arquitectura como herramientas para la realización de proyectos responsables, tanto con la sociedad como con los ecosistemas.
Claudia Marcela Ruge, Amparo Quijano, Camilo Ayala   +2 more
doaj  

Combination of indirect measurements to improve sigmal estimation [PDF]

, 2000
A form to combine two kinds of indirect measurements to be processed together is proposed for illconditioned problems. Linear individual measurements with unknown proportionality constants jointly considered determine a unique non-linear problem.
Elicabe, Guillermo Enrique, Frontini, Gloria Lia   +1 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Estudio de un caso de control interno

Telos: Revista de Estudios Interdisciplinarios en Ciencias Sociales, 2005
El estudio se efectuó con el objetivo de analizar el control interno en el Almacén de la Facultad de ciencias Económicas y Sociales de la Universidad del Zulia. La metodología fue descriptiva. Se utilizó como población a todo el personal del almacén. Los
Alfonso Pirela
doaj  

Elaboración de un modelo didáctico: base para la realización eficiente de la tarea docente

Revista Española de Pedagogía
La complejidad del proceso de enseñanza-aprendizaje exige que el profesor reflexione profundamente sobre él. Para facilitar su tarea le hemos ofrecido un modelo didáctico basado en una determinada metodología, que implica una concepción sistemática del ...
Antonio Medina Rivilla
doaj   +1 more source

La cultura materiale

, 2011
Gli studi sulla cultura materiale nell'esperienza dell'archeologia medievale italiana (e dell'archeologia italiana in genere).
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Evaluando el rendimiento en la tabla de golpeo del makiwara

Revista de Artes Marciales Asiáticas, 2012
No hay en la literatura estudios que cuantifiquen las características del impacto en las tablas del makiwara. Lógicamente, la evaluación de las características mecánicas de varios diseños de tablas de makiwara debería ser un paso inicial en la ...
Paul K. Smith, Timothy Niiler, Peter W. McCullough   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source