Results 141 to 150 of about 568,984 (259)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

New contributions to the local-State dinamic in the archaeological site Villavil (Hualfín, Catamarca, Argentina) [PDF]

open access: yes, 2014
El presente trabajo expone información preliminar de las actividades realizadas en el sitio arqueológico Villavil, ubicado al norte del valle de Hualfín, Belén, Catamarca, sobre una meseta aluvial a 1850 msnm.
Lynch, Julieta
core   +1 more source

THE FEASIBILITY OF PROTECT REBARS AGAINST CORROSION USING LOCALLY AVAILABLE MATERIALLS IN EGYPT [PDF]

open access: yesThe International Conference on Civil and Architecture Engineering, 2012
openaire   +1 more source

Comportamiento productivo al aire libre y en invernadero de híbridos entre materiales locales de berenjena (Solanum melongena)

open access: yes, 2006
Los híbridos de berenjena (Solanum melongena L.) son las variedades predominantes para cultivo en invernadero en nuestro país (Prohens et al., 2005a). La selección y desarrollo de híbridos para cultivo en invernadero ha permitido obtener materiales con una buena adaptación a las estas condiciones.
Muñoz-Falcón, Julio   +3 more
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Proyecto adecuación de nave industrial para la instalación de una fábrica de embutidos [PDF]

open access: yes, 2004
Se realizará un estudio de la ingeniería de la producción de productos del cerdo (embutidos), el diseño de la obra civil, instalaciones e infraestructuras, las bases para la redacción del informe medioambiental e implantación del futuro sistema de ...
Sebastian Garcia, Julia Maria
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

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