Results 151 to 160 of about 2,047,298 (354)

Principles for Accountable Leadership — The AA1000 Series [PDF]

open access: yes, 2012
Author Daniel Waistell, Standards Manager of London-based AccountAbility, has provided the most recent benchmarks of identifying stakeholders for businesses to pursue greater sustainability in their respective operations.
Waistell, Daniel
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Introduction:Materials, materiality and material culture [PDF]

open access: yes
This introduction advocates for the expansion of Tibetan studies by embracing new sources, methodologies and frameworks to better understand the material culture of Tibet and the Himalayas. We start by reviewing the current state of the discipline’s engagement with material culture.
Brox, Trine, Martin, Emma, Lange, Diana
openaire   +1 more source

Effect of Bipolar Plate Materials on Performance of Fuel Cells

open access: green, 2018
Tabbi Wilberforce   +5 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Zasada istotności w raportowaniu niefinansowym

open access: yesPrace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu, 2019
The main objective of the paper is to compare approaches to the materiality principle with regard to reporting on CSR and sustainable development as well as integrated reporting.
Joanna Dyczkowska
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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