Results 91 to 100 of about 2,886,615 (308)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Enhanced Tribological and Bacterial Resistance of Carbon Nanotube with Ceria- and Silver-Incorporated Hydroxyapatite Biocoating

Nanomaterials, 2018
Pertaining to real-life applications (by scaling up) of hydroxyapatite (HA)-based materials, herein is a study illustrating the role of carbon nanotube (CNT) reinforcement with ceria (CeO2) and silver (Ag) in HA on titanium alloy (TiAl6V4) substrate ...
Aditi Pandey, Anup Kumar Patel, Ariharan S., Vikram Kumar, Rajeev Kumar Sharma, Satish Kanhed, Vinod Kumar Nigam, Anup Keshri, Arvind Agarwal, Kantesh Balani   +9 more
doaj   +1 more source

Constitutive Models Based on Compressible Plastic Flows [PDF]

, 1983
The need for describing materials under time or cycle dependent loading conditions has been emphasized in recent years by several investigators. In response to the need, various constitutive models describing the nonlinear behavior of materials under ...
Rajendran, A. M.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Discovery of a new zinc oxide semiconductor: 21R polytype

Structural Dynamics
Zinc oxide (ZnO) is a notable semiconductor with a range of interesting electronic and optical properties. Polytypic behavior of crystal structures can strongly affect the properties of materials, especially in ZnO.
Matej Fonović, Jelena Zagorac, Maria Čebela, Dragana Jordanov, Dejan Zagorac   +4 more
doaj   +1 more source

Review of the Integration of Fused Filament Fabrication with Complementary Methods for Fabricating Hierarchical Porous Polymer Structures

Applied Sciences
Hierarchically porous polymers can unite macro-scale architected voids with micro-scale pores, enabling unique combinations of low density, high surface area, and controlled transport properties that are difficult to achieve with traditional methods ...
Savvas Koltsakidis, Dimitrios Tzetzis
doaj   +1 more source

Thermal Insulation Performance of Aerogel Nano-Porous Materials: Characterization and Test Methods. [PDF]

Gels, 2023
Lou F, Dong S, Zhu K, Chen X, Ma Y.
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A new bin size index method for statistical analysis of multimodal datasets from materials characterization. [PDF]

Sci Rep, 2023
Jiang T, Luo S, Wang D, Li Y, Wu Y, He L, Zhang G.   +6 more
europepmc   +1 more source