Results 81 to 90 of about 1,337,621 (234)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Interdisciplinary research on the nature and properties of ceramic materials [PDF]

open access: yes
Several investigations concerning the properties and processing of brittle ceramic materials as related to design considerations are briefly described. Surface characterization techniques, fractography, high purity materials, creep properties, impact and

core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Improving the seismic resistance of masonry buildings : concepts for cultural heritage and recent developments in structural analysis [PDF]

open access: yes, 2007
Conservation and restoration of historical structures are still a challenge to modern practitioners even if considerable research advances have occurred in the last decades, namely with respect to non-destructive testing, mechanical characterization ...
Lourenço, Paulo B., Oliveira, Daniel V.
core  

Effect of the image resolution on the statistical descriptors of heterogeneous media

open access: yes, 2017
The characterization and reconstruction of heterogeneous materials, such as porous media and electrode materials, involve the application of image processing methods to data acquired by microscopy techniques.
Barbosa, Romeli   +2 more
core   +1 more source

Advanced techniques for characterizing bioinspired materials

open access: yes, 2017
Understanding materials’ analytical techniques is a key feature to ensure efficient material development and to fully evaluate their functional properties. Biobased materials are emergent materials that are attracting attention due to their outstanding properties, pushing forward their use in a wide range of applications going from biomedical and ...
Machado, Raul, Sencadas, Vitor
openaire   +4 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Analytical techniques for characterization of raw materials in cell culture media

open access: yesBMC Proceedings, 2011
Raw materials are a critical part of any cell culture medium; therefore, it is of utmost importance to understand and characterize them for high-quality product.
Sharma Chandana   +4 more
doaj   +1 more source

Characterization Techniques for Materials’ Properties Measurement [PDF]

open access: yes, 2010
The objective of the work is to point on an important part in nowadays electronic domain and that is, the characterization of materials; a necessary process before integrating them in electronic devices such as, tunable filters and tunable phase shifters.
Kassem, Hussein   +2 more
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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