Results 91 to 100 of about 996,284 (341)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Fortnite & Chemistry [PDF]

open access: yesarXiv, 2020
In this activity, we describe how the video game Fortnite provides a nice opportunity for students to think about chemistry. The game has a survival system based on the acquisition and use of items, which has interesting chemical and physical properties.
arxiv  

Controlling basal plane sulfur vacancy in water splitting MoSx/NiF electrocatalysts through electric-field-assisted pulsed laser ablation

open access: yesiScience, 2023
Summary: Eco-friendly, efficient, and durable electrocatalysts from earth-abundant materials are crucial for water splitting through hydrogen and oxygen generation.
Chaudry Sajed Saraj   +8 more
doaj  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Organic compounds in metallic hydrogen [PDF]

open access: yes
Metallic hydrogen is the most common condensed material in the universe, comprising the centre of gas giant planets. However, experimental studies are extremely challenging, and most of our understanding of this material has been led by theory. Chemistry in this environment has not been probed experimentally, so here we examine hydrocarbon chemistry in
arxiv   +1 more source

Compositional and Interface Engineering of Organic-Inorganic Lead Halide Perovskite Solar Cells

open access: yesiScience, 2020
Power conversion efficiency (PCE) of the perovskite solar cells (PSCs) has remarkably been increased from 3.1% to 25.2%. The fast expansion of the PSCs has been along with the development of compositional and interface engineering, which has been playing
Haizhou Lu   +4 more
doaj  

Hydrolytically stable foamed HKUST-1@CMC composites realize high-efficient separation of U(VI)

open access: yesiScience, 2021
Summary: HKUST-1@CMC (HK@CMC) composites that show good acid and alkali resistance and radiation resistance were successfully synthesized by introducing carboxymethyl cellulose (CMC) onto the surface of HKUST-1 using a foaming strategy.
Dejun Zeng   +7 more
doaj  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Lecture Notes on the Statistical Mechanics of Disordered Systems [PDF]

open access: yesarXiv, 2017
This material complements David Chandler's Introduction to Modern Statistical Mechanics (Oxford University Press, 1987) in a graduate-level, one-semester course I teach in the Department of Chemistry at Duke University. Students enter this course with some knowledge of statistical thermodynamics and quantum mechanics, usually acquired from ...
arxiv  

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