Results 151 to 160 of about 2,293,436 (352)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Rapid start-up of carbon-free H2 production by ammonia oxidative decomposition over Co/Ce0.5Zr0.5O2 with microwave irradiation

open access: yesiScience
Summary: Hydrogen is a promising combustion improver for use with ammonia fuels, but a cost-effective method for easily producing hydrogen from ammonia at a high rate has yet to be developed.
Takahiro Matsunaga   +4 more
doaj   +1 more source

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics. [PDF]

open access: yesACS Pharmacol Transl Sci, 2021
Balasubramaniam B   +8 more
europepmc   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Chemical- and green-precursor-derived carbon dots for photocatalytic degradation of dyes

open access: yesiScience
Summary: Rapid industrialization and untreated industrial effluents loaded with toxic and carcinogenic contaminants, especially dyes that discharge into environmental waters, have led to a rise in water pollution, with a substantial adverse impact on ...
Inderbir Kaur   +5 more
doaj   +1 more source

Computational chemistry [PDF]

open access: yes
With the advent of supercomputers, modern computational chemistry algorithms and codes, a powerful tool was created to help fill NASA's continuing need for information on the properties of matter in hostile or unusual environments.
Arnold, J. O.
core   +1 more source

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