Results 161 to 170 of about 2,293,436 (352)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Editorial for "Materials Chemistry" Section, in Journal Molecules. [PDF]

Molecules, 2020
Malucelli G.
europepmc   +1 more source

Studies on Localization of “Histidine-Rich” Peptide Material Present in Epidermis of the Newborn Rat**From the Departments of Dermatology, Industrial Health and Biological Chemistry and the Institute of Industrial Health, The University of Michigan, Ann Arbor.

, 1967
Jorge J. Gumucio, Carolyn S. Feldkamp, I.A. Bernstein   +2 more
openalex   +1 more source

The evolution of chemistry: A history of its ideas, methods, and materials (Farber, Eduard) [PDF]

, 1970
George B. Kauffman
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

RADIATION CHEMISTRY OF MATERIALS USED IN PLUTONIUM PROCESSING.

, 1969
A. R. Kazanjian, Alistair K. Brown
openalex   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Chiral Triptycenes in Supramolecular and Materials Chemistry. [PDF]

ChemistryOpen, 2020
Preda G, Nitti A, Pasini D.
europepmc   +1 more source

Furfural as a Raw Material of Organic Synthetic Chemistry

, 1961
Yoshikazu Hachihama, Toshiyuki Shono
openalex   +2 more sources

A combinatorial approach to metamaterials discovery

Some fifteen years ago a paper reporting a combinatorial approach to materials discoveries revolutionized materials research and other disciplines such as chemistry and pharmacology [1].
Chen, W.T., Fedotov, V.A., Plum, E., Tanaka, K., Tsai, D.P., Zheludev, N.I.   +5 more
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