The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
CHEMICAL ENGINEERING DIVISION FUELS AND MATERIALS CHEMISTRY SEMIANNUAL REPORT, JULY--DECEMBER 1971.
Paul Blackburn+7 more
openalex +2 more sources
Triptycene-like naphthopleiadene as a readily accessible scaffold for supramolecular and materials chemistry. [PDF]
Amin MK+6 more
europepmc +1 more source
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Structural material anomaly detection system using water chemistry data. V. Impurity ions balance evaluation based on conductivity data and its application to water chemistry diagnosis in BWR plants. [PDF]
Yamato ASAKURA+8 more
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Machine learning descriptors in materials chemistry used in multiple experimentally validated studies: Oliynyk elemental property dataset. [PDF]
Lee S, Chen C, Garcia G, Oliynyk A.
europepmc +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Structural Material Anomaly Detection System Using Water Chemistry Data, (VII) [PDF]
Makoto Nagase+3 more
openalex +1 more source