Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
Introduction to the <i>RSC Advances</i> themed collection on the photoluminescence of lanthanide-doped phosphor materials. [PDF]
Yadav RS, Richards BS, Pisarska J, Ye X.
europepmc +1 more source
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source
Correction: Green synthesis of gum Arabic-activated magnetite-nickel nanoparticles for selective removal of Cd(ii) and Cu(ii) from complex aqueous systems. [PDF]
Taha EH +5 more
europepmc +1 more source
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Multicomponent reactions IV. [PDF]
Müller TJJ, Chebanov VA.
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High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
PMSE Centennial: Celebration of Success and New Frontiers in Polymer Materials Science and Engineering. [PDF]
Grunlan MA +11 more
europepmc +1 more source
Editorial: The landscape of the metal complexes: relevant properties and potential applications. [PDF]
Piccinelli F +2 more
europepmc +1 more source
Correction: Yu et al. Application of NIR Fluorescent Materials in Imaging and Treatment of Tumors of Different Depths. <i>Nanomaterials</i> 2025, <i>15</i>, 811. [PDF]
Yu M +6 more
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