Results 141 to 150 of about 1,676,767 (268)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Composite Materials Engineering Graduating Class Photograph: 2004

open access: yes, 2004
This is a class photograph of the Composite Materials Engineering Graduating Class of 2004 at Winona State University. The students in the photograph are: Brian Bentler, Brian Dietz, Katrina Gass-Callahan, Brian Gunderson, Michael Haas, Tyler Jessie ...
Composite Materials Engineering Department-Winona State University
core  

Retracted: Control Method of Nanomaterial Numerical Control Electronic Processing Based on RBF Neural Network

open access: yesAdvances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Composite Materials Engineering Graduating Class Photograph: 2010

open access: yes, 2010
This is a class photograph of the Composite Materials Engineering Graduating Class of 2010 at Winona State University. The students in the photograph are: Jesse Dulek, Matthew Frahm, Dylan Fritz, Ryan Gleason, Jack Hendrickson, Kyle Hoffmann, Christopher
Composite Materials Engineering Department-Winona State University
core  

Retracted: Effect of Using Modern Banking Services on Customer Inspiration: Statistical Analysis

open access: yesAdvances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy