E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Advances in Materials Science and Engineering, 2023 Advances in Materials Science and Engineering
doaj +1 more source
The Advent of Molecular Targeted Therapies Against Cancer. Toward Multi-Targeting Drugs Through Materials Engineering: A Possible Future Scenario. [PDF]
Small SciPuzzo M +4 more
europepmc +1 more source
A Multidisciplinary and Multicultural Adventure: From Materials Engineering to Cardiovascular Science. [PDF]
Circ Res, 2017 Serpooshan V.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Retracted: Development of Novel Nano-Silver-Based Antenna for Green Agriculture
Advances in Materials Science and Engineering, 2023 Advances in Materials Science and Engineering
doaj +1 more source
Are X-rays the key to integrated computational materials engineering? [PDF]
IUCrJ, 2015 Ice G.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding. [PDF]
J Vis Exp, 2018 Cavallo G +4 more
europepmc +1 more source
Advances in hole transport materials engineering for stable and efficient perovskite solar cells
, 2017 Z. H. Bakr +5 more
semanticscholar +1 more source