Results 181 to 190 of about 10,926,875 (269)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Retracted: Influences of Aqueous Nanofluid Emulsion on Diesel Engine Performance, Combustion, and Emission: IoT (Emission Monitoring System)

Advances in Materials Science and Engineering
Advances in Materials Science and Engineering
doaj   +1 more source

Retracted: Structural Classification of Basalt FRP at High Temperatures

Advances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

Modulating Microbial Materials - Engineering Bacterial Cellulose with Synthetic Biology. [PDF]

ACS Synth Biol
Malcı K, Li IS, Kisseroudis N, Ellis T.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Retracted: Construction and Performance Research of Reinforced Iron-Based Powder Metallurgy Materials Based on Phyllanthin as Drug Transport Carriers

Advances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

Materials engineering by ameloblasts. [PDF]

J Dent Res, 2015
Habelitz S.
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Retracted: Modified Mechanical Structure Electric Bike Design Computation and Prototype Model Implementation

Advances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

The Advent of Molecular Targeted Therapies Against Cancer. Toward Multi-Targeting Drugs Through Materials Engineering: A Possible Future Scenario. [PDF]

Small Sci
Puzzo M, De Santo M, Morelli C, Leggio A, Pasqua L.   +4 more
europepmc   +1 more source