Results 171 to 180 of about 1,402,582 (408)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Development and mechanical properties of construction materials from lunar simulant [PDF]

Development of versatile engineering materials from locally available materials in space is an important step toward the establishment of outposts on the Moon and Mars.
Desai, Chandra S.
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Investigating the Physical Adsorption of DCPD/Furfural and H₂ Adsorption–Dissociation Behaviors in RE-MOFs

Molecules
Metal–organic frameworks (MOFs) have emerged as promising catalysts in the hydrogenation of bicyclopentadiene (DCPD) and furfural. The physical adsorption behaviors of substrate molecules and H2 within the pore structures of MOFs significantly influence ...
Muye Niu, Zuoshuai Xi, Chenhui He, Wenting Ding, Shanshan Cheng, Juntao Zhang, Hongyi Gao   +6 more
doaj   +1 more source

Harmonizing Nature, Engineering, and Creativity: An Interdisciplinary Exploration of Engineered Living Materials, Artistry, and Sustainability in Collaborative Mycelium Brick Construction

IOCB 2024
This study presents an innovative approach to interdisciplinary education by integrating principles of biology, engineering and art to foster holistic learning experiences for children. The focus lies on assembling mycelium bricks as engineered living materials with promising applications in sustainable construction. Through a collaborative group task,
Richard W. van Nieuwenhoven, Matthias Gabl, Ruth Mateus-Berr, Ille C. Gebeshuber   +3 more
openaire   +2 more sources

Lunar Resource Assessment: an Industry Perspective [PDF]

The goals of the U.S. space program are to return to the Moon, establish a base, and continue onward to Mars. To accomplish this in a relatively short time frame and to avoid the high costs of transporting materials from the Earth, resources on the Moon ...
Altenberg, B. H., Feldman, S. C., Franklin, H. A.   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Crystal engineering construction of caffeic acid derivatives with potential applications in pharmaceuticals and degradable polymeric materials

, 2020
Zhihan Wang, Quinton Flores, Hongye Guo, Raquel Trevizo, Xiaochan Zhang, Shihan Wang   +5 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Optimization of production of construction materials assortment based on system engineering methods

, 2018
Darya Krivogina
openalex   +1 more source