Results 171 to 180 of about 2,982,518 (386)
Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
Design and Reprogrammability of Zero Modes in 2D Materials from a Single Element [PDF]
Mechanical extremal materials, a class of metamaterials that exist at the bounds of elastic theory, possess the extraordinary capability to engineer any desired elastic behavior by harnessing mechanical zero modes -- deformation modes that demand minimal or no elastic energy.
arxiv
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source
Magnesium oxysulfate (MOS) cement, with its low carbon footprint, faces challenges in water resistance and volume stability. This study examines how fly ash (FA) and ground granulated blast-furnace slag (GGBS) improve MOS cement properties. Findings show
Yasong Zhao+5 more
doaj
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang+5 more
wiley +1 more source
Uniaxial‐Oriented Perovskite Films with Controllable Orientation
Perovskite films with large crystal size, preferred orientation, and facile fabrication process, combining advantages of single‐crystal and polycrystalline films, have gained considerable attention recently. However, there is little research on the facet
Dongni Li+9 more
doaj +1 more source
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel+4 more
wiley +1 more source
Geomaterials as construction aggregates: a state-of-the-art
R. Přikryl
semanticscholar +1 more source