Results 31 to 40 of about 1,418,690 (312)

How to Build a Wind Turbine: Introducing Fourth Graders to Engineering in KidWind Project [PDF]

, 2019
With colored construction paper, Styrofoam cups, coffee filters, cereal boxes, empty toilet paper rolls, and straws splayed across the desks, Mrs. McCanna’s fourth grade classroom filled with excited chatter as her students constructed small-scale wind ...
Dell\u27Agnese, Courtney
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Recent Progress in Doped g-C3N4 Photocatalyst for Solar Water Splitting: A Review

Frontiers in Chemistry, 2022
Graphitic carbon nitride (g-C3N4) photocatalysis for water splitting is harvested as a fascinating way for addressing the global energy crisis. At present, numerous research subjects have been achieved to design and develop g-C3N4 photocatalysis, and the
Yilong Yang, Wantong Niu, Liyun Dang, Yanli Mao, Junshu Wu, Kaidong Xu   +5 more
doaj   +1 more source

Sustainable engineering of rammed earth construction. Material, design and performances optimization

, 2023
Les bâtiments du futur doivent répondre à des exigences de plus en plus élevées en matière de performances énergétiques et de durabilité environnementale, pour l'ensemble des chaînes de production et construction. Cette question a suscité un vif intérêt vers l’utilisation de matériaux naturels comme la terre crue dans la construction, caractérisée par ...
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Spontaneous hierarchical surface engineering of minerals through coupled dissolution‐precipitation chemistry

Aggregate
Peculiar hierarchical microstructures in creatures inspire modern material design with distinct functionalities. Creatures can effortlessly construct sophisticated yet long‐range ordered microstructure across bio‐membrane through ion secretion and ...
Jinyang Jiang, Jiawen Zhang, Lanxin Wang, Zeyu Lu, Fengjuan Wang, Zhiyong Liu, Hongbo Zeng   +6 more
doaj   +1 more source

Geotechnical Engineering Properties of Fly Ash and Bottom Ash: Use as Civil Engineering Construction Material

Engineer: Journal of the Institution of Engineers, Sri Lanka, 2018
Norochcholai coal power plant is the largest coal power plant in Sri Lanka and during the combustion of coalit annually generates about 250,000 metric tons of coal ash which consists of fly ash (FA) and bottom ash (BA). Almost all the generated ash is disposed into ash dumps except a small quantity of FA (30%) that is effectively utilized.
P. G. S. Gimhan, J. P. B. Disanayaka, M. C. M. Nasvi   +2 more
openaire   +2 more sources