Results 41 to 50 of about 3,113,641 (244)
Materials science and ontologies
This chapter starts by discussing the challenges in material innovation for manufacturing and the need for multidisciplinary approaches involving actors from many different communities. Interoperability is a key to address these challenges. The new paradigm of materials digitalisation is introduced, and how this can be supported by ontologies ...
Jesper Friis +4 more
openaire +3 more sources
NONLINEARITY IN MATERIALS SCIENCE
We discuss the all-important issue of nonlinearity in the physical sciences, with emphasis on its importance in condensed matter physics, where nonlinearity provides a natural mechanism for selective trapping of excitations, such as electrons, at a microscopic scale.
openaire +3 more sources
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Advances in Materials Science and Engineering
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Advances in Materials Science and Engineering
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Retracted: Tribological Behavior of AA7075 Reinforced with Ag and ZrO2 Composites
Advances in Materials Science and Engineering
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Advances in Materials Science and Engineering
doaj +1 more source

