Results 81 to 90 of about 3,585,944 (313)
Advances in Materials Science and Engineering
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Teaching sustainable development in materials science and engineering [PDF]
Preparing the next generation of materials scientists and engineers requires more than teaching them knowledge of material properties and behaviors. Materials science and engineering must also take into account materials sustainability in the context of ...
Lesar, Richard, Chen, K. C., Apelian, D.
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Advances in Materials Science and Engineering
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Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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Advances in Materials Science and Engineering
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Electrically tunable dielectric materials and strategies to improve their performances
Electrically tunable dielectric materials have potential applications as various microwave devices, such as tunable oscillators, phase shifters and varactors High dielectric tunability, low dielectric loss tangent and appropriate level of dielectric ...
Li, S. +5 more
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