Results 141 to 150 of about 6,329,131 (258)

A skin-mimicking multifunctional hydrogel via hierarchical, reversible noncovalent interactions. [PDF]

Sci Adv
Guo X, Zhang S, Patel S, Sun X, Zhu YL, Wei Z, Wang R, He X, Wang Z, Yu C, Tan SC.   +10 more
europepmc   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Effect of Cr:Al Ratio on Corrosion Mechanism of Ni-Cr-Mo-Al Alloys in 3.5 wt.% NaCl Solution: Microstructure and Electrochemical and Passive Characteristics. [PDF]

Materials (Basel)
Lian C, Xie W, Fang H, Wang W, Yu J, Li J, He X.   +6 more
europepmc   +1 more source

Synthesis and characterization of sulfide-based ceramic, glassy and glass-ceramic materials used as Electrolytes in All-Solid-State batteries

, 2013
The use of liquid electrolytes in Li-ion secondary batteries raises several safety issues because of their flammability. Fifty years ago, the replacement of these electrolytes by inorganic solid compounds lead to the development of a new generation of batteries, the so-called “All-Solid State” Batteries.In this manuscript, we describe the synthesis and
openaire   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Tunneling spectroscopy of Andreev bands in multiterminal graphene-based Josephson junctions. [PDF]

Sci Adv
Jung W, Jin S, Park S, Shin SH, Watanabe K, Taniguchi T, Cho GY, Lee GH.   +7 more
europepmc   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Monolayer TiAlTe₃: A Perfect Room-Temperature Valleytronic Semiconductor. [PDF]

Materials (Basel)
Jia K, Zhang CW, Wang ZR, Wang PJ.
europepmc   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Theoretical Insights into Hydrogen Production from Formic Acid Catalyzed by Pt-Group Single-Atom Catalysts. [PDF]

Materials (Basel)
Jin T, Liang S, Zhang J, Li Y, Bai Y, Wu H, Razanau I, Pan K, Wang F.   +8 more
europepmc   +1 more source