Results 111 to 120 of about 8,899,666 (297)

Materials testing, 1950s -- 03

, 1950
Materials ...
Geo. Desmyth Photo
core  

Motion-induced eddy current testing of composite materials [PDF]

, 2016
Modern composite materials are gaining more and more importance in mechanical engineering. Due to the complex structure of most of these materials, traditional NDT methods do not satisfy the measurement requirements.
Weise, Konstantin, Ziolkowski, Marek, Schmidt, Reinhard, Mengelkamp, Judith, Gorges, Stephan, Brauer, Hartmut, Carlstedt, Matthias   +6 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Materials testing, 1960s -- 13

, 1960
Materials ...
[Swinburne Technical College]
core  

Effect of tool material on joint quality in friction stir welding of aluminum-steel tailor welded blanks

Journal of Advanced Joining Processes
Friction stir welding (FSW) enables high-strength joints between dissimilar materials such as aluminum and steel and is particularly suited for hybrid tailor welded blanks in deep drawing.
Robin Göbel, Maximilian Keppler, Stefan Weihe, Martin Werz   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Thickness debit effect of Ni-based single crystal superalloy thin-walled specimens in the VHCF regime based on a vibration fatigue test

Journal of Materials Research and Technology
This paper proposes a novel vibration fatigue testing methodology of thin-walled specimens in the very high cycle fatigue (VHCF) regime, with the lifetime up to 109 cycles. A series of novel thin-walled specimens for the single crystal superalloy DD6 are
Wei Xu, Beichen Zhu, Xin Chen, Yue Zhang, Yuhuai He   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Data considered by Committee c-1 of the American Society for Testing Materials, in preparing the standard specifications and tests for Portland cement (serial designation c 9 = 17) of the American Society for Testing Materials, including the first and second reports of the Joint Conference on Uniform Methods of Tests and Standard Specifications for Cement.

, 1919
Conference of representatives of the American Society of Civil Engineers, the American Society for testing Materials, and the United States government.Various pagings.Mode of access ...
American Society for Testing Materials
core