Results 141 to 150 of about 24,530,151 (408)

Advances in induction-heated plasma torch technology [PDF]

open access: yes, 1972
Continuing research has resulted in significant advances in induction-heated plasma torch technology which extend and enhance its potential for broad range of uses in chemical processing, materials development and testing, and development of large ...
Poole, J. W., Vogel, C. E.
core   +1 more source

Thickness debit effect of Ni-based single crystal superalloy thin-walled specimens in the VHCF regime based on a vibration fatigue test

open access: yesJournal of Materials Research and Technology
This paper proposes a novel vibration fatigue testing methodology of thin-walled specimens in the very high cycle fatigue (VHCF) regime, with the lifetime up to 109 cycles. A series of novel thin-walled specimens for the single crystal superalloy DD6 are
Wei Xu   +4 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

A thickness debit effect characterization parameter for creep rupture behaviors of nickel-based single crystal superalloys

open access: yesJournal of Materials Research and Technology
Creep rupture tests were conducted on 67 thin-walled DD6 specimens, with thicknesses ranging from 0.35 mm to 1.50 mm, at temperatures of 760 °C, 850 °C, 980 °C, and 1100 °C, revealing a log-linear relationship between rupture lifetimes and specimen ...
Yue Zhang   +5 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Evaluation of fasteners and fastener materials for space vehicles [PDF]

open access: yes
Testing of fasteners, bolts, rivets, and fastener materials - high temperature ...
Glackin, J. J., Gowen, E. F., Jr.
core   +1 more source

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