Results 141 to 150 of about 4,033,138 (351)

The effects of cutting parameters on cutting forces and heat generation when drilling animal bone and biomechanical test materials

, 2017
Akos Cseke, Robert Heinemann
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Vacuum lamination of photovoltaic modules [PDF]

Vacuum lamination of terrestrial photovoltaic modules is a new high volume process requiring new equipment and newly develop materials. Equipment development, materials research, and some research in related fields and testing methods are ...
Burger, D. R.
core   +1 more source

Erosion-corrosion behaviour of Zirconia WC-6Co, WC-6Ni and SS316 [PDF]

, 2015
The current study investigates a ceramic, two cermets and a metal under solid-liquid impingement with 3.5% NaCl and 150mg/l hydraulic fracturing sand at two extreme angles of impact, 90° and 20°.
Andrews, N., Galloway, A. M., Giourntas, L., Pearson, A.   +3 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Microshear Bond Strength of Composite to Dentin Using Self-etch and Etch and Rinse Adhesives – A Systematic Review and Meta-analysis

Journal of International Clinical Dental Research Organization
Objectives: A systematic review was conducted to determine whether bonding with self-etch (SE) adhesive system is more effective as compared to etch-and-rinse (ER) adhesive system.
Tanvi Sanjay Satpute, Sanjyot Mulay, Divya Naik   +2 more
doaj   +1 more source

Materials technology advancement program for expandable manned space structures Summary report [PDF]

Composite materials testing for fire resistant wall structures for expandable manned space ...
Cordier, K. L., Cross, W. B.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Avaliação histológica de hidroxiapatita sintética associada a fosfato de cálcio (?-TCP) utilizados em levantamento de assoalho de seio maxilar

Revista de Odontologia da UNESP
Introdução: Quando a altura do osso alveolar residual é insuficiente na região posterior da maxila, a elevação do assoalho do seio maxilar visando a viabilizar a instalação de implantes dentários é um procedimento indicado.
Luis Gustavo Jaime Paiva, Aline Carvalho Batista, Leandro Cardoso de Carvalho, Robson Rodrigues Garcia   +3 more
doaj   +1 more source