Results 171 to 180 of about 4,033,138 (351)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Test liner paper and folding carton from some lignocellulosic materials

open access: gold, 2015
Iosr Journals   +4 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Penerapan Metode Pengujian White-box, Black-box dan User Acceptance Testing (UAT) pada website laser.umm.ac.id. [PDF]

open access: yes
Universitas Muhammadiyah Malang (UMM) developed an application providing efficient search tools and sorting options to help users find the books or information needed quickly, namely the laser.umm.ac.id application or OPAC | Online Public Access Catalog.
Isnaini, Rahayu
core  

Development of a trace-based approach for elastic characterization of multi-material composite pipes: Theory and testing [PDF]

open access: gold
Rubén Edgardo López   +3 more
openalex   +1 more source

Supplementary Material for: The Single-Matrix Digit Cancellation Test (SMDCT), a screener for selective attention deficits: standardization in an Italian population sample and clinical usability in acute stroke patients

open access: gold, 2023
Fabrizio Pasotti   +10 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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