Results 211 to 220 of about 4,042,136 (301)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Studies on the Possibility of Introducing New Materials into Reproductive Biotechnology and a New Type of Catheter for Embryo Transfer. [PDF]

Animals (Basel)
Wieczorek J, Stodolak-Zych E, Okoń K, Koseniuk J, Bryła M, Kotula-Balak M, Jura J, Poniedziałek-Kempny K, Rajska I, Soból K, Lasoń-Kubarek A, Krakowska I, Fraś G.   +12 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Adapting mainstreaming genetic education and clinical communication materials for cancer patients of varying backgrounds. [PDF]

Patient Educ Couns
Christian-Afflu SN, Sheikh R, Strang A, Chicaiza AM, Oliveros S, Barthelus E, Pagan-Lopez I, Lynch KA, Diamond LC, Gonzalez CJ, Offit K, Robson ME, Liu YL, Gonsky JP, Bulone L, Stadler ZK, Hay JL, Hamilton JG.   +17 more
europepmc   +1 more source

ABLATION MATERIAL TESTING. [PDF]

, 1968
openaire   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Author Correction: Boosting mechanical durability under high humidity by bioinspired multisite polymer for high-efficiency flexible perovskite solar cells. [PDF]

Nat Commun
Li Z, Jia C, Wan Z, Cao J, Shi J, Xue J, Liu X, Wu H, Xiao C, Li C, Li M, Zhang C, Li Z.   +12 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

A hybrid machine learning approach for predicting the flexural strength of concrete reinforced with waste aluminium fibres. [PDF]

Sci Rep
Boursas F, Boufarh R, Altowaijri Y, Bakri M, Abderrahmani S.   +4 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source