Results 71 to 80 of about 6,601 (223)

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open access: yesSalud Pública de México, 2017
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Equipo editorial SPM
doaj  

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

open access: yesiNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen   +6 more
wiley   +1 more source

[Quality of life of Medicine students of the National University of Córdoba, Argentina] [PDF]

open access: yesRev Fac Cien Med Univ Nac Cordoba, 2023
Gobbi CA   +5 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi   +13 more
wiley   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro   +5 more
wiley   +1 more source

3D‐Printed Models in Oral Surgery Simulation Training: A Scoping Review

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Background Advancements in three‐dimensional (3D) printing have introduced innovative tools for medical and dental education. In dental surgery, 3D‐printed simulation models offer valuable presurgical training. This review explores the scope, study types, key findings, limitations, and future research needs to enhance their application in ...
Shahrzad Rahimizadeh Nahavandi   +5 more
wiley   +1 more source

Índice por materias

open access: yesSalud Pública de México, 2016
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doaj  

Seasonal Predictions and Their Applications in the Mediterranean Region: Part I—Sources of Predictability and Prediction Skill

open access: yesInternational Journal of Climatology, EarlyView.
The ability to predict climate fluctuations at seasonal timescales offers significant socio‐economic benefits. However, limited understanding of predictability mechanisms and model errors hinders forecast quality. Recent research has improved forecasting systems and data quality.
Gualdi Silvio   +12 more
wiley   +1 more source

4D Printable Formulations of Mixed Low and High Molecular Weight Liquid Crystalline Units: A Versatile Route to Functional Soft Actuators

open access: yesMacromolecular Rapid Communications, EarlyView.
This work presents a practical approach for formulating 4D printable inks that incorporates substantial fractions of low molecular weight mesogens. By blending low molecular weight diacrylate or monoacrylate constituents with a high molecular weight main‐chain macromer, the resulting mixture proves suitable for direct ink writing, enabling mechanical ...
Lorena Ceamanos   +5 more
wiley   +1 more source

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