Results 41 to 50 of about 128,635 (269)

Pasando la Turquesa: Objetos Azules del Valle de Ónavas, Sonora, México

Clio Arqueológica, 2020
En el Valle de Ónavas, Sonora, México, en la zona media del río Yaqui, se encontraron varias piezas de verde claro a un material de color verde o azul intenso visualmente identificado turquesa durante un trabajo de campo realizado allí en 2004.
Emiliano Gallaga Murrieta, Emiliano Ricardo Melgar Tísoc   +1 more
doaj   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Estudio de las diferentes rutas de síntesis renovables para la producción de Caprolactama

Dyna, 2018
No existen métodos para la síntesis biobasada directa de la caprolactama (CPL), la combinación de la producción biotecnológica de materias primas renovables con modificaciones por procesos físicos y químicos están emergiendo y mostrando resultados ...
Diego Alejandro Trujillo-Vera, Yesid Vélez-Salazar   +1 more
doaj   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

Advanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren, Qian Yue, Ning Gao, Qiu‐Lian Hao, Yan Huo, Chuchu Li, Xinyue Leng, Lu‐Lu Sun, Maggie Pui Man Hoi, Hai‐Hao Han, Mingliang Ma, Xu‐Wen Li   +11 more
wiley   +1 more source

Confitería, chocolatería y sus materias primas [PDF]

, 2015
11p.BIBLIOGRAFIA http://www.portafolio.co/economia/consumo-chocolate-colombia http://chocospot.obolog.es/materias-primas-elaboracion-chocolate-664596 abc.es/sociedad/el chocolate en peligro de extinción http://www.pnud.org.co/img_upload ...
Mahecha Lancheros, Julie Pauline
core  

Engineering Borophene Band Structure Through Thickness

Advanced Science, EarlyView.
Borophene grown on W(110) shows a thickness‐dependent evolution of its structural and electronic properties. Surface microscopy, diffraction, XPS, and ARPES reveal distinct monolayer and bilayer phases. The formation of the second layer is accompanied by structural reconstruction, changes in chemical properties, and new ARPES features, demonstrating ...
Matteo Jugovac, Marcin Szpytma, Tevfik Onur Menteş, Andrea Locatelli, Iulia Cojocariu   +4 more
wiley   +1 more source

Formulação, preparação e caracterização de massas porcelânicas baseadas em diopsídio natural [PDF]

, 2005
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência e Engenharia de Materiais.As indústrias do setor cerâmico, em particular aquelas produtoras de revestimentos cerâmicos, louça de ...
Piccoli, Rosaura
core  

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

Advanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen, Xinying Fu, Wenqian Dong, Xiaobei Deng, Simin Chen, Fujun Wang, Jian Zhao, Shiqun Shao, Liqiang Fan, Jingyu Zhang, Lixin Zhang   +10 more
wiley   +1 more source

Ruralidade: definições e tipologias

Gestão e Desenvolvimento, 1996
O termo rural tem significados diferentes para diferentes pessoas. Desde uma paisagem bucólica até zonas remotas, atrasadas e com tradições ancestrais, passando por lugares onde se produzem alimentos e matérias-primas para o sector secundário, tudo cabe ...
Francisco José Lopes de Sousa Diniz
doaj   +1 more source