Results 321 to 330 of about 2,787,926 (407)

Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms

British Journal of Clinical Pharmacology, EarlyView.
Aim To characterize pharmacokinetic changes of sertraline and its metabolite during pregnancy and postpartum, and their relationship to maternal postpartum depressive symptoms. Methods This was a prospective observational, longitudinal study of pregnant women with a major depressive disorder treated with sertraline (N = 185 women, 205 pregnancies ...
Sílvia M. Illamola, Zachary N. Stowe, Marc L. Kalin, Michael D. Evans, Catherine M. Sherwin, Maged M. Costantine, D. Jeffrey Newport, James C. Ritchie, Angela K. Birnbaum   +8 more
wiley   +1 more source

Lipid pathways connecting maternal BMI with infant obesity risk. [PDF]

Sci Rep
George AD, Wang T, Duong T, Schooneveldt Y, Paul S, Olshansky G, Mansell T, Saffery R, Vuillermin P, Ponsonby AL, Burgner D, Barwon Infant Study Investigator Group, Burugupalli S, Meikle PJ.   +13 more
europepmc   +1 more source

Physiologically based pharmacokinetic model combined with a clinical lactation study to determine doravirine concentrations in human breastmilk

British Journal of Clinical Pharmacology, EarlyView.
Aims To determine breastmilk concentrations of doravirine via PBPK modelling in combination with a clinical lactation study. As women living with HIV are not able to cease antiretroviral therapy during lactation, it is necessary to establish drug transfer into breastmilk to determine exposure of the infant to antiretroviral drugs and potential risk of ...
Lena van der Wekken‐Pas, David Burger, Rick Greupink, Angela Colbers   +3 more
wiley   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Association of Intended Mode of Delivery With Neonatal and Maternal Outcomes at 22-25 Weeks of Gestation. [PDF]

O G Open
Hamilton JL, McGee PL, Sibai BM, Varner MW, Tita ATN, Longo M, Bell EF, Stoll BJ, Thorp JM, Reddy UM, Frey HA, Miller ES, Rouse DJ, Simhan HN, Bailit JL, Dugoff L, Saade GR, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.   +17 more
europepmc   +1 more source

Inapparent maternal ZIKV infection impacts fetal brain development and postnatal behavior. [PDF]

PLoS Pathog
Chou TW, McCourt M, Marmut E, Karuppusamy V, Lindman M, Estevez I, Buckley BD, Thackray JK, Rodriguez K, Nissenbaum M, Mishra C, Atkins C, Kusnecov AW, Tischfield MA, Daniels BP.   +14 more
europepmc   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

What work-up do we need for women with congenital heart disease in the 21st century for the preparation of pregnancy? [PDF]

JRSM Cardiovasc Dis
Bakalis S, Douglas H.
europepmc   +1 more source

Prenatal paracetamol exposure and wheezing in infancy: a targeted maximum likelihood estimation application. [PDF]

BMJ Open Respir Res
Moccia C, Zugna D, Popovic M, Moirano G, Pizzi C, Migliore E, Fariselli P, Sanavia T, Rusconi F, Nybo Andersen AM, Richiardi L, Maule M.   +11 more
europepmc   +1 more source